Sandra Bullock and Ryan Reynolds will star in Most Wanted. The action comedy stars Reynolds as an FBI agent who is escorting a criminal suspect (Bullock) to court when they are ambushed and forced to go on the run. The duo starred last year in The Proposal. Most Wanted not only reunites Bullock and Reynolds, but also Proposal director Anne Fletcher, writer Pete Chiarelli, and producers David Hoberman and Todd Lieberman.